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Selection of the Appropriate Assay

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Objectives

  • List the general assays (HLA typing; HLA-directed antibody identification and specificity; crossmatch; other immune assays) used in the histocompatibility and immunogenetics laboratory
  • Describe the purpose of each general assay
  • Discuss the variations of each general assay and the advantages and disadvantages of each variation
  • Select the appropriate assay based on the intended purpose (e.g., level of resolution, sensitivity, limitations)