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Overview of the HLA System

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Objectives:

  • Compare and contrast the properties of the HLA class I and class II proteins
  • Describe the role that HLA plays in immune response to pathogens
  • Describe HLA polymorphism and HLA haplotypes
  • Describe situations where HLA plays a part in the risk of a disease or in its treatment and in the outcome of transplantation of cells, tissues and organs