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Overview of the Complement System

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Objectives:

Following this lecture, students should be able to:

  • Define the complement system
  • List the three complement pathways
  • Describe at what point the three pathways converge
  • List which class and subclasses of antibody can bind complement
  • Define how complement is important in the CDC assay
  • List reasons to test for complement
  • Describe the role of complement in transplantation