×

Error message

Unfortunately, at this time the feature that links the CE's from ASHI-U to Learning Builder is currently disabled.  You will have to check the box that you don't have an ABHI Account.  You can complete the Modules on ASHI-U but you will have to manually input the CE's into Learning Builder.  We are so sorry for the inconvenience.  We are working diligently to get this issue resolved as soon as possible.

Killer-cell Immunoglobulin-like Receptor (KIR) Genotyping

Select a ModuleModule DetailsReview MaterialsTake QuizEvaluate ModulePrint Certificate

Objectives:
• Explain the role of killer cell immunoglobulin-like receptors in detecting the loss of HLA class I on the cell surface
• Utilize KIR nomenclature
• List the KIR genes and the ligands of the key inhibitory KIR proteins
• Be able to predict KIR haplotypes
• Discuss why KIR genotyping may be useful in a clinical setting
• Be familiar with methodologies for detecting the presence or absence of KIR genes and defining KIR alleles
• Understand and identify the ASHI standards that pertain to various KIR genotyping assays, and the quality control measures that must be incorporated into the test system.