HLA and Infectious Diseases
-Describe the antigen presentation pathways for class I and class II HLA molecules
-Define the meaning of “T cell epitope” and describe why epitopes from the same pathogen might vary among individuals
-Describe the complex interaction between HLA and pathogens that:
-Has shaped the HLA profile of the human population and
-Impacts the evolution of a pathogen.
-Identify other receptors (Killer Immunoglobulin-like Receptor (KIR), Leukocyte Immunoglobulin-like Receptor (LILR)) that bind HLA and may impact infection