The Basics of Allorecognition

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Objectives:

  • Define terms for various donor sources and outcomes of transplantation
  • Describe the targets of the immune response to transplanted tissue/cells/organs
  • Compare and contrast the three pathways of allorecognition of allo-MHC molecules by T lymphocytes
  • Describe the role of antibodies in rejection
  • List strategies to control the extent of allorecognition in transplantation