The Basics of Allorecognition
Objectives:
- Define terms for various donor sources and outcomes of transplantation
- Describe the targets of the immune response to transplanted tissue/cells/organs
- Compare and contrast the three pathways of allorecognition of allo-MHC molecules by T lymphocytes
- Describe the role of antibodies in rejection
- List strategies to control the extent of allorecognition in transplantation